Publications

Authors:

Villa, Irene; Vedda, Anna; Cantarelli, Irene Xochilt; Pedroni, Marco; Piccinelli, Fabio; Bettinelli, Marco Giovanni; Speghini, Adolfo; Quintanilla, Marta; Vetrone, Fiorenzo; Rocha, Ueslen; Jacinto, Carlos; Carrasco, Elisa; Rodríguez, Francisco Sanz; Juarranz, Ángeles; del Rosal, Blanca; Ortgies, Dirk H.; Gonzalez, Patricia Haro; Solé, José García; García, Daniel Jaque

Title:

1.3 μm emitting SrF2:Nd3+ nanoparticles for high contrast in vivo imaging in the second biological window

Year:

2015

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

NANO RESEARCH

ISSN of journal:

1998-0124

N° Volume:

8

Number or Folder:

2

Page numbers:

649-665

Keyword:

fluorescence imaging; nanomedicine; rare earth doped nanoparticles

Short description of contents:

Novel approaches for high contrast, deep tissue, in vivo fluorescence biomedical imaging are based on infrared-emitting nanoparticles working in the so-called second biological window (1,000–1,400 nm). This allows for the acquisition of high resolution, deep tissue images due to the partial transparency of tissues in this particular spectral range. In addition, the optical excitation with low energy (infrared) photons also leads to a drastic reduction in the contribution of autofluorescence to the in vivo image. Nevertheless, as is demonstrated here, working solely in this biological window does not ensure a complete removal of autofluorescence as the specimen’s diet shows a remarkable infrared fluorescence that extends up to 1,100 nm. In this work, we show how the 1,340 nm emission band of Nd3+ ions embedded in SrF2 nanoparticles can be used to produce autofluorescence free, high contrast in vivo fluorescence images. It is also demonstrated that the complete removal of the food-related infrared autofluorescence is imperative for the development of reliable biodistribution studies

Product ID:

95249

Handle IRIS:

11562/955457

Last Modified:

June 29, 2023

Bibliographic citation:

Villa, Irene; Vedda, Anna; Cantarelli, Irene Xochilt; Pedroni, Marco; Piccinelli, Fabio; Bettinelli, Marco Giovanni; Speghini, Adolfo; Quintanilla, Marta; Vetrone, Fiorenzo; Rocha, Ueslen; Jacinto, Carlos; Carrasco, Elisa; Rodríguez, Francisco Sanz; Juarranz, Ángeles; del Rosal, Blanca; Ortgies, Dirk H.; Gonzalez, Patricia Haro; Solé, José García; García, Daniel Jaque, 1.3 μm emitting SrF2:Nd3+ nanoparticles for high contrast in vivo imaging in the second biological window «NANO RESEARCH» , vol. 8 , n. 2 , 2015 , pp. 649-665

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo