Publications

Authors:

Darra, Elena; Bovi, Michele; Perduca, Massimiliano; F., Vivian; Romeo, Alessandro; Monaco, Ugo Luigi; Mariotto, Sofia Giovanna

Title:

Inclusion of α-bisabolol into PLGA nanoparticles enhances its pro-apoptotic activity in human tumoral pancreatic cells.

Year:

2013

Type of item:

Poster

Tipologia ANVUR:

Poster

Language:

Inglese

Format:

A Stampa

Congresso:

NANOTECHITALY 2013

Place:

Venice

Period:

27-29/11/2013

Page numbers:

---

Keyword:

PLGA nanoparticles; Alfa-Bisabolol; Pro-apoptotic activity

Short description of contents:

Alfa-Bisabolol (figure 1), a sesquiterpene alcohol present in essential oils derived from a variety of plants, presents pro-apoptotic activity against several human cancer cell lines. Its poor aqueous solubility limits in vitro and in vivo tests. Herein we report a study of the formulation and characterization of alfa-Bisabolol using poly lactide-co-glycolid acid copolymer nanoparticles (PLGA/B). The human therapeutic treatment of PLGA is approved by US Food and Drug Administration (USFDA) thanks to its biocompatibility. This copolymer is one of the most successfully used in nanomedicine applications since it is hydrolyzed in the body to produce the biodegradable lactic and glycolic acid monomers

Product ID:

78753

Handle IRIS:

11562/640554

Deposited On:

December 4, 2013

Last Modified:

November 1, 2022

Bibliographic citation:

Darra, Elena; Bovi, Michele; Perduca, Massimiliano; F., Vivian; Romeo, Alessandro; Monaco, Ugo Luigi; Mariotto, Sofia Giovanna, Inclusion of α-bisabolol into PLGA nanoparticles enhances its pro-apoptotic activity in human tumoral pancreatic cells.  in NANOTECHITALY 2013 , Proceedings of "NANOTECHITALY 2013" , Venice , 27-29/11/2013 , 2013 , pp. ---

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