Publications

Authors:

Mohammed Esseddik, Toumi; Rebai, Redouane; Kebaili, Fethi Farouk; Merouane, Fateh; Boulahrouf, Khaled; Bahri, Laid; Perduca, Massimiliano; Necib, Youcef

Title:

In Vivo Immunomodulatory Potential of Partial Purified Lectin from the Saffron Milk Cap Mushroom, Lactarius deliciosus (Agaricomycetes), against Colloidal Carbon Particles

Year:

2020

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS

ISSN of journal:

1521-9437

N° Volume:

22

Number or Folder:

11

Page numbers:

1043-1055

Keyword:

Lectin, Lactarius deliciosus, phagocytic activity, half time of life of carbon particles, carbon clearance, reticulo-endothelial system, medicinal mushrooms

Short description of contents:

Mushrooms compounds and biomolecules are known for their biological beneficial effect and dietary properties. Theirs molecules are using at immunology for the ability to stimulate immune cells and biotherapy of diseases. In this study, the immunomodulatory effect using carbon clearance test in vivo of partial purified lectins of Lactarius deliciosus using DEAE-Sephacyl column, with sugar affinity against galactose, methyl-B.D galactopyranoside and lactose, specify showed a significant effect on phagocytic activity and half time of life of carbon particles in mice with different concentrations (5, 10, 15 and 30mg/kg). The results showed that: the immunomodulatory effect increased in low doses and decreased after in high doses as compared with the control group p< 0.0001. L. deliciosus lectin exerted a dose-dependent immunostimulant activity at the reticulo-endothelial system, phagocytic activity on macrophages and neutrophils in spleen and liver against the carbon colloidal.

Product ID:

116641

Handle IRIS:

11562/1026179

Last Modified:

November 15, 2022

Bibliographic citation:

Mohammed Esseddik, Toumi; Rebai, Redouane; Kebaili, Fethi Farouk; Merouane, Fateh; Boulahrouf, Khaled; Bahri, Laid; Perduca, Massimiliano; Necib, Youcef, In Vivo Immunomodulatory Potential of Partial Purified Lectin from the Saffron Milk Cap Mushroom, Lactarius deliciosus (Agaricomycetes), against Colloidal Carbon Particles «INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS» , vol. 22 , n. 11 , 2020 , pp. 1043-1055

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