Cellular and molecular mechanisms of diseases - BASI MOLECOLARI DI MALATTIA (2015/2016)

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Course code
4S000675
Name of lecturer
Barbara Cellini
Number of ECTS credits allocated
6
Academic sector
BIO/10 - BIOCHEMISTRY
Language of instruction
Italian
Location
VERONA
Period
II semestre dal Mar 1, 2016 al Jun 10, 2016.

To show the organization of the course that includes this module, follow this link * Course organization

Lesson timetable

II semestre
Day Time Type Place Note
Tuesday 8:30 AM - 10:30 AM lesson Lecture Hall H from Mar 8, 2016  to Jun 10, 2016
Thursday 8:30 AM - 10:30 AM lesson Lecture Hall L from Mar 10, 2016  to Jun 10, 2016

Learning outcomes

Understanding of the molecular mechanisms of various pathological states, with particular emphasis on genetic diseases. Correlate the alterations at molecular level with the pathological manifestations of the diseases at cell, tissue and patient level. Define the molecular basis of the available treatments as well as of the strategies to be developed.

Syllabus

-Molecular pathology of proteins: introduction and general concepts
-Hemoglobin molecular pathology
-Collagen molecular pathology
-Diseases linked to protein aggregation
-Disorders due to alterations of ABC transporters: cystic fibrosis
-Inherited metabolic diseases: disorders of the carbohydrate, lipids, amino acids and nucleotide metabolism.
-Mitochondrial diseases
-Lysosomal storage diseases
-Peroxisomal diseases
-Diseases linked to ER stress
-Innovative therapeutic approaches to the cure of protein deficits
-Mechanisms of action of bacterial toxis
-Disorders linked to the production of free radicals

Assessment methods and criteria

Oral test

STUDENT MODULE EVALUATION - 2015/2016