Activity | Credits | Period | Academic staff | Timetable |
---|---|---|---|---|
teoria | 3 | II sem. | Alejandro Giorgetti | |
laboratorio | 3 | II sem. | Alejandro Giorgetti |
This course gives an introduction to molecular computational biology, from biomolecular simulation and to structural bioinformatics.
Part A – Bioinformatics
− Advanced Structural Bioinformatics
- Thermodynamic basis of the stability of folded biomolecular structure
− Molecular basis of human perception
Part B – Molecular Modeling
− Basic elements of molecular modeling
− Electrostatic modeling
− Energy minimization based on force fields
− Molecular dynamics: solution by using the open source NAMD and/or Gromacs codes
− Conformational analysis
Part C – Ligand-prtoein interactions
− Protein assembly (protein-protein complexes, protein-protein interactions in protein dimers, crystals): protein-protein docking algorithms and programs
− Ligand Protein interaction: docking algorithms and programs
− Projects: Drug and/or protein design
Written
Title | Format (Language, Size, Publication date) |
ligando | octet-stream (it, 2 KB, 18/05/15) |
proteina | octet-stream (it, 102 KB, 18/05/15) |
slides-dock | pdf (it, 2872 KB, 18/05/15) |
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