Pubblicazioni

Autori:

Darra, Elena; Bovi, Michele; Perduca, Massimiliano; F., Vivian; Romeo, Alessandro; Monaco, Ugo Luigi; Mariotto, Sofia Giovanna

Titolo:

Inclusion of α-bisabolol into PLGA nanoparticles enhances its pro-apoptotic activity in human tumoral pancreatic cells.

Anno:

2013

Tipologia prodotto:

Poster

Tipologia ANVUR:

Poster

Lingua:

Inglese

Formato:

A Stampa

Titolo del Convegno:

NANOTECHITALY 2013

Luogo:

Venice

Periodo:

27-29/11/2013

Intervallo pagine:

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Parole chiave:

PLGA nanoparticles; Alfa-Bisabolol; Pro-apoptotic activity

Breve descrizione dei contenuti:

Alfa-Bisabolol (figure 1), a sesquiterpene alcohol present in essential oils derived from a variety of plants, presents pro-apoptotic activity against several human cancer cell lines. Its poor aqueous solubility limits in vitro and in vivo tests. Herein we report a study of the formulation and characterization of alfa-Bisabolol using poly lactide-co-glycolid acid copolymer nanoparticles (PLGA/B). The human therapeutic treatment of PLGA is approved by US Food and Drug Administration (USFDA) thanks to its biocompatibility. This copolymer is one of the most successfully used in nanomedicine applications since it is hydrolyzed in the body to produce the biodegradable lactic and glycolic acid monomers

Id prodotto:

78753

Handle IRIS:

11562/640554

depositato il:

4 dicembre 2013

ultima modifica:

1 novembre 2022

Citazione bibliografica:

Darra, Elena; Bovi, Michele; Perduca, Massimiliano; F., Vivian; Romeo, Alessandro; Monaco, Ugo Luigi; Mariotto, Sofia Giovanna, Inclusion of α-bisabolol into PLGA nanoparticles enhances its pro-apoptotic activity in human tumoral pancreatic cells.  in NANOTECHITALY 2013 , Atti di "NANOTECHITALY 2013" , Venice , 27-29/11/2013 , 2013 , pp. ---

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