Pubblicazioni

Autori:

Cortinovis, Gaia; Vincenzi, Leonardo; Anderson, Robyn; Marturano, Giovanni; Marsh, Jacob Ian; Bayer, Philipp Emanuel; Rocchetti, Lorenzo; Frascarelli, Giulia; Lanzavecchia, Giovanna; Pieri, Alice; Benazzo, Andrea; Bellucci, Elisa; Di Vittori, Valerio; Nanni, Laura; Ferreira Fernández, Juan José; Rossato, Marzia; Aguilar, Orlando Mario; Morrell, Peter Laurent; Rodriguez, Monica; Gioia, Tania; Neumann, Kerstin; Alvarez Diaz, Juan Camilo; Gratias, Ariane; Klopp, Christophe; Bitocchi, Elena; Geffroy, Valérie; Delledonne, Massimo; Edwards, David; Papa, Roberto

Titolo:

Adaptive gene loss in the common bean pan-genome during range expansion and domestication

Anno:

2024

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

NATURE COMMUNICATIONS

ISSN Rivista:

2041-1723

N° Volume:

15

Numero o Fascicolo:

1

Intervallo pagine:

1-15

Parole chiave:

P. vulgaris, pangenome, domestication

Breve descrizione dei contenuti:

The common bean (Phaseolus vulgaris L.) is a crucial legume crop and an ideal evolutionary model to study adaptive diversity in wild and domesticated populations. Here, we present a common bean pan-genome based on five high-quality genomes and whole-genome reads representing 339 genotypes. It reveals similar to 234 Mb of additional sequences containing 6,905 protein-coding genes missing from the reference, constituting 49% of all presence/absence variants (PAVs). More non-synonymous mutations are found in PAVs than core genes, probably reflecting the lower effective population size of PAVs and fitness advantages due to the purging effect of gene loss. Our results suggest pan-genome shrinkage occurred during wild range expansion. Selection signatures provide evidence that partial or complete gene loss was a key adaptive genetic change in common bean populations with major implications for plant adaptation. The pan-genome is a valuable resource for food legume research and breeding for climate change mitigation and sustainable agriculture.

Pagina Web:

https://www.nature.com/articles/s41467-024-51032-2

Id prodotto:

141928

Handle IRIS:

11562/1143866

ultima modifica:

29 gennaio 2025

Citazione bibliografica:

Cortinovis, Gaia; Vincenzi, Leonardo; Anderson, Robyn; Marturano, Giovanni; Marsh, Jacob Ian; Bayer, Philipp Emanuel; Rocchetti, Lorenzo; Frascarelli, Giulia; Lanzavecchia, Giovanna; Pieri, Alice; Benazzo, Andrea; Bellucci, Elisa; Di Vittori, Valerio; Nanni, Laura; Ferreira Fernández, Juan José; Rossato, Marzia; Aguilar, Orlando Mario; Morrell, Peter Laurent; Rodriguez, Monica; Gioia, Tania; Neumann, Kerstin; Alvarez Diaz, Juan Camilo; Gratias, Ariane; Klopp, Christophe; Bitocchi, Elena; Geffroy, Valérie; Delledonne, Massimo; Edwards, David; Papa, Roberto, Adaptive gene loss in the common bean pan-genome during range expansion and domestication «NATURE COMMUNICATIONS» , vol. 15 , n. 1 , 2024 , pp. 1-15

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