The goal of the Structural Biology course for the degree in Bioinformatics and Medical Biotechnology is to develop in the student the skills necessary to critically read and assess scientific papers in this branch of science. After an introduction discussing the relative weight of the different techniques used to determine the three-dimensional structure of biomolecules, the course concentrates on the theory and practice of macromolecular crystallography. The fundamentals of the theory of diffraction, the modern methods of data collection and the phase problem are covered in detail. In addition, papers selected from the current literature dealing with important biological structures are read and discussed.
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