Synthetic Biology (2020/2021)

Learning outcomes

Prof. Nicola Vitulo-UNIVR ( Nicola.Vitulo@unifi.it)
Genome analysis
- Genome assembly and quality assessement for different applications.
- Gene prediction and annotation.
- Identification of Variants respect to a reference (WT) genome: analysis of mutant genomes.
- Variant prioritization and genotype to phenotype association.
- Transcript analysis on WT and mutants.
Prof. Marco Fondi-UNIFI ( Marco.Fondi@unifi.it)
– metabolic pathway reconstruction and simulation.
- Integration of metabolomic/protemic/transpictomic data.
- Flux balance analysis
Prof. Olaf Kruse - UNI-BIELEFELD/ CEBITECH (olaf.kruse@uni-bielefeld.de)
- Examples of metabolic pathway design and construction (general)
- Engineering of artifical CO2 fixation.
- Designing green cell factories
- Designing metabolite processing pathways in heterothrophyc systems.