Fundamentals of biotechnological processes and plants (2018/2019)



Course code
4S02707
Credits
6
Coordinator
David Bolzonella
Academic sector
ING-IND/25 - CHEMICAL PLANTS
Language of instruction
Italian
Teaching is organised as follows:
Activity Credits Period Academic staff Timetable
teoria 5 I semestre David Bolzonella

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laboratorio 1 I semestre David Bolzonella

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Learning outcomes

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MM: teoria
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The course of Fundamentals of Bioprocess Engineering aims at transferring to students the basic knowledge about transport phenomena (matter, energy and momentum transfer) as well as the methodology for mass and energy balances around bioreactors operating both in batch and continuous mode for industrial production. These aspects are essential basic information for future courses on the same topic at master level.
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MM: laboratorio
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The course of Fundamental of Bioprocess Engineering is formed of two modules: one frontal teaching activity (5 CFU) and the lab activity (1 CFU). The lab activity is orientated to the transfer of practical knowledge for the solution of quantitative problems.

Syllabus

------------------------ MM: teoria ------------------------ Main contents of the class course will be: 1. Introduction The basic elements like the use of units, scheme representations, including P&ID, or some examples of industrial production will be given 2. Fundamentals Transport phenomena for mass, energy and momentum. Mass transfer will include a focus on interphase transfer as in the case of oxygen in water. The Oxygen Transfer Efficiency (OTE) will be defined. Mixing, type of impellers, baffles, mixing time 3. Bioreactors Different types of bioreactors, discontinuous (batch) and continuous (CSTR, PFR), will be described. The basic equations and the conditions of stable operation will be defined. Different yields will be defined. 4. Bioreactor facilities The main facilities for the bioreactor, like mixers and correspondent time of mixing and power, aeration and oxygen transfer mechanisms and efficiency will be studied. Monitoring and control systems based on physical-chemical signals like pH, redox, OD will be described. ------------------------ MM: laboratorio ------------------------ The lab activities will consider two different experiences regarding both transport phenomena and bioprocesses (definition of yields and kinetics). The experimental data collected during the lab activity will be used to produce two reports about the lab experiences carried out.

Assessment methods and criteria

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MM: teoria
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The final examination will consist of two parts: a written and an oral test. The written exam will be made of three parts, two numerical exercise and one theoretical open question. After evaluation of the written part an oral exam will be given. The reports deriving from the lab experiences will be part of the evaluation.
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MM: laboratorio
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Different groups of students will produce the reports on the lab experience. The evaluation of the reports will be used together with the results of the written and oral examination to form the final mark.

Reference books
Activity Author Title Publisher Year ISBN Note
teoria Pauline M. Doran Bioprocess Engineering Principles Academic Press 1995 0-12-220855-2
laboratorio Pauline M. Doran Bioprocess Engineering Principles Academic Press 1995 0-12-220855-2

STUDENT MODULE EVALUATION - 2017/2018