The course aims at giving a general overview on biological features and clinical application of embryonic, fetal and adult stem cells. Hematopoietic stem cell transplantation, bone marrow microenvironment in normal and pathological hematopoiesis and problems related to stem cell-based approaches to regenerative medicine are particularly developed and discussed.
- INTRODUCTION TO STEM CELLS - EMBRIOLOGY and ORGANOGENESIS - EMBRYONIC STEM CELLS (ESCs) and INDUCED PLURIPOTENT STEM CELLS (iPSCs) - HEMATOPOIETIC STEM CELLS (HSCs) - LEUKEMIA STEM CELLS (LSCs) - MESENCHYMAL STROMAL CELLS (MSCs) - STROMA & CANCER - EXTRACELLULAR VESICLES - NOTCH & WNT PATHWAYS - CARDIAC and LUNG STEM CELLS - NEURAL STEM CELLS - GOOD MANUFACTURING PRACTICE
| Author | Title | Publisher | Year | ISBN | Note |
| Gian Paolo Bagnara | Cellule Staminali (Edizione 2) | Esculapio | 2013 | 978-88-7488-997-6 |
16 lessons, 3 hours each (total: 48 hours):
Final exam: oral
