The course aims at furnishing the theoretical and technological basis to approach the study of protein functions.
The course integrates proteomic strategies, target identification, biochemical interaction analysis, protein arrays, informatics-based interaction prediction to address the investigation of the proteinogenic changes that underlie the disease pathomechanisms, with examples based on selected diseases.
Characteristics of protein, proteomes and proteomics
Bioinformatic interacting networks
Native MS analysis
Protein enrichment methods
Biochemical approaches to protein protein interaction
Identification of new therapeutical targets in breast cancer
All the supporting material (slides and research papers) will be found on the online platform.
|Ciborowski P. and Silberring J.||Proteomic profiling and analytical chemistry: the crossroads.||Elsevier||2013||978-0-444-59378-8|
The exam is conceived to evaluate the acquisition of the concepts and methodologies addressed at the functional proteome study.
The exam is based on three open questions to be answered in written mode (2 hours time).
Discussion of the replies is always welcomed.
Cà Vignal 1, Strada Le Grazie 15, 37134 Verona
VAT number 01541040232
Italian Fiscal Code 93009870234
© 2020 | Verona University | Credits