Clinical proteomics (2016/2017)

Course code
4S003688
Name of lecturer
Daniela Cecconi
Coordinator
Daniela Cecconi
Number of ECTS credits allocated
6
Academic sector
CHIM/01 - ANALYTICAL CHEMISTRY
Language of instruction
English
Location
VERONA
Period
I sem. dal Oct 3, 2016 al Jan 31, 2017.

Lesson timetable

I sem.
Day Time Type Place Note
Wednesday 1:30 PM - 3:30 PM lesson Lecture Hall B  
Friday 11:30 AM - 1:30 PM lesson Lecture Hall H  

Learning outcomes

The aim of clinical proteomics is actually to find molecular signatures, to describe affected pathways and possibly identify candidate biomarkers that can help in the diagnosis, prognosis and prediction of therapeutic outcomes and elucidate pathogenic mechanisms.

Clinical proteomics course aims to give an overview of proteomics methodologies and their application to current areas of clinical investigation.

Syllabus

CLINICAL PROTEOMICS
Introduction to clinical proteomics.
Strategies for protein sample preparation.
Gel-based and gel-free clinical proteomics analyses.
Protein Identification by Tandem Mass Spectrometry.
Label-Based MS clinical proteomic approaches.
Advances in clinical proteomics research for biomarkers discovery.
Clinical Proteomics for elucidating the mechanism of action of anticancer drugs.
Clinical Proteomics to study Pancreatic Cancer Stem Cells
Hepcidin assay and clinical application
Recent Advances in Cardiovascular disease

Assessment methods and criteria

The final exam includes the presentation of a scientific paper and a written exam that will cover all the topics of the program.

STUDENT MODULE EVALUATION - 2016/2017