Functional proteomics (2016/2017)

Course code
4S003659
Name of lecturer
Alessandra Maria Bossi
Coordinator
Alessandra Maria Bossi
Number of ECTS credits allocated
6
Academic sector
CHIM/01 - ANALYTICAL CHEMISTRY
Language of instruction
English
Period
I sem. dal Oct 3, 2016 al Jan 31, 2017.

Lesson timetable

I sem.
Day Time Type Place Note
Tuesday 3:30 PM - 5:30 PM lesson Lecture Hall A  
Thursday 1:30 PM - 3:30 PM lesson Lecture Hall F  

Learning outcomes

The course aims at furnishing the theoretical and technological basis to approach the study of protein functions.
The course integrates proteomic strategies, target identification, biochemical interaction analysis, protein arrays, informatics-based interaction prediction to address the investigation of the proteinogenic changes that underlie the disease pathomechanisms, with examples based on selected diseases.

Syllabus

Definitions of proteome and proteomics
Proteomic platforms
Bioinformatic interacting networks
Protein arrays
imaging SPR
native MS analysis
protein enrichment methods
biochemical approaches to protein protein interaction
crosstalk tumor-microambient
identification of new therapeutical targets in breast cancer


Assessment methods and criteria

Written, 2 hours time, open questions

STUDENT MODULE EVALUATION - 2016/2017