Clinical molecular biology (2016/2017)

Course code
4S003670
Name of lecturer
Martina Montagnana
Coordinator
Martina Montagnana
Number of ECTS credits allocated
6
Academic sector
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY
Language of instruction
English
Period
I sem. dal Oct 3, 2016 al Jan 31, 2017.

Lesson timetable

I sem.
Day Time Type Place Note
Friday 8:30 AM - 10:30 AM lesson Lecture Hall B from Oct 7, 2016  to Jan 31, 2017

Learning outcomes

The course aims to make students understand the role of genetic testing in the clinical course of the patient.
The course also aims to provide students who have no medical training the basic knowledge on the clinical aspects concerning the genetic basis of diseases.
The course aims to provide an updated view of molecular biology techniques that are used in a clinical setting.

Syllabus

Classroom lessons with some methodological insights done at the Molecular Biology Laboratory.
Topics:
• Introduction and organization of the molecular biology laboratory
• The coagulation cascade; thrombophilia and deep vein thrombosis
• Mendelian inheritance: Hemocromatosis
• Mendelian inheritance: Cystic fibrosis
• Male infertility and Y microdeletions
• Prenatal diagnosis of genetic disease
• Genetic diseases and mental retardation
• Molecular biology in oncohematological diseases
• Genetics of hemoglobinopathies
• Pharmacogenetics

Reference books
Author Title Publisher Year ISBN Note
Neri G e Genuardi M Genetica Umana e Medica (Edizione 3) EDRA LSWR - Masson 2014 978-88-217-3743-4

Assessment methods and criteria

Written test, with open questions and multi choice questions.
The aim of the test is to verify the understanding of the arguments inserted in the program of the course.
The contents of the written test will be represented by topics contained in the teaching program.

STUDENT MODULE EVALUATION - 2016/2017